Trained in clinical pathology at the National Institutes of Health, Russ served on the permanent NIH staff as a practicing molecular biologist and molecular pathologist. In the course of his later career, Russ has worked extensively in optimal health, nutrition, oriental medicine, and color and music therapy. He was the founding chairman of the Scientific Committee of the American Holistic Medical Association. In 1984, Dr. Jaffe developed the lymphocyte response assays (LRA) by ELISA/ACT tests. These tests enable physicians to examine the responses of patients’ immune systems to challenges. He is also the founder of Perque, a nutritional supplement company.